Involvement of Monocarboxylate Transporter 4 Expression in Statin-Induced Cytotoxicity
نویسندگان
چکیده
منابع مشابه
Monocarboxylate transporter expression in mouse brain.
Although glucose is the major metabolic fuel needed for normal brain function, monocarboxylic acids, i.e., lactate, pyruvate, and ketone bodies, can also be utilized by the brain as alternative energy substrates. In most mammalian cells, these substrates are transported either into or out of the cell by a family of monocarboxylate transporters (MCTs), first cloned and sequenced in the hamster. ...
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In this study, the expression and distribution of monocarboxyolate transporter 1 (MCT1) along the intestines (duodenum, jejunum, ileum, cecum, colon and rectum) of dogs were investigated at both the mRNA and protein levels. The expression of MCT1 protein and its distribution were confirmed by Western blotting and immunohistochemical staining using the antibody for MCT1. We identified mRNA codin...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2016
ISSN: 0022-3549
DOI: 10.1016/j.xphs.2016.01.014